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queG [2019-07-25 10:22:06]
function
synthesis of queuosine, tRNA modification
product
epoxyqueuosine reductase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]Gene
Coordinates
967,935 969,095
The protein
Catalyzed reaction/ biological activity
conversion of epoxyqueuosine to queuosine [Pubmed|21502530]Protein family
QueG family (single member, according to UniProt)[SW|Cofactors]
cobalaminFe-S cluster [Pubmed|21502530]Structure
[PDB|5D08] [Pubmed|27638883]Expression and Regulation
Operons
genes
[gene|3F22BD8DB7BEC2701B960546AC683603DFCADCCE|queG]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-A241 (yhbA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/241 NBRP B. subtilis, Japan]BKE08910 ([gene|3F22BD8DB7BEC2701B960546AC683603DFCADCCE|queG]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTGCACAGCCTCCT, downstream forward: _UP4_TGACATACGTATAGAGCAGABKK08910 ([gene|3F22BD8DB7BEC2701B960546AC683603DFCADCCE|queG]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08910 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTGCACAGCCTCCT, downstream forward: _UP4_TGACATACGTATAGAGCAGAReferences
26230193,21502530,27638883